Raw Powder B7-33 H2-relaxin Releasing Hormone Peptide
B7-33 is a synthetic single-chain peptide derived from the B-chain of human H2-relaxin, a peptide hormone known for its roles in tissue repair, anti-fibrosis, vasodilation, and anti-inflammatory signaling.
- Product Introduction
What Is B7-33 (H2-Relaxin Releasing Hormone Peptide)?
B7-33 is a synthetic single-chain peptide derived from the B-chain of human H2-relaxin, a peptide hormone known for its roles in tissue repair, anti-fibrosis, vasodilation, and anti-inflammatory signaling.
Unlike native relaxin (a two-chain peptide structure), B7-33 is engineered as a simplified, stable, and cost-effective analog that retains the beneficial anti-fibrotic and cytoprotective activities of H2-relaxin - without the unwanted pro-fibrotic side effects sometimes associated with full-length relaxin.
It primarily acts through the RXFP1 receptor, stimulating ERK1/2 signaling without activating cAMP, making it a safer and more targeted relaxin-mimetic peptide for advanced research applications.
How B7-33 Works
Selective RXFP1 Activation
B7-33 binds to the RXFP1 receptor, similar to native relaxin, but activates only the ERK signaling pathway, not cAMP.
This reduces adverse effects and makes it more predictable for laboratory models.
Anti-Fibrotic Activity
The peptide reduces:
- Collagen deposition
- Tissue scarring
- Myofibroblast activation
It is highly valuable in studies on heart, lung, liver, and skin fibrosis.
Anti-Inflammatory & Cytoprotective Effects
B7-33 helps
- Decrease inflammatory cytokines
- Reduce oxidative damage
- Support cellular recovery
Mimics Beneficial Relaxin Effects Without Full Complexity
It captures relaxin's tissue-repair and organ-protective functions in a simpler, stable structure that is easier to synthesize and study.
B7-33 Benefits
- Reduces fibrosis and scar tissue formation
- Promotes tissue regeneration and cell repair
- Improves blood vessel relaxation (vasodilation)
- Exhibits anti-inflammatory behavior
- Protects organs (heart, lungs, liver) from injury-related stress
- Provides relaxin-like benefits with fewer side pathways
Order B7-33 peptide now – Limited Stock Available!
High-purity (≥99%) peptide for research. Limited stock available with fast, discreet worldwide shipping. Contact us for bulk or wholesale inquiries.
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