
Anti-Wrinkle Raw Powder Acetyl Hexapeptide-8 CAS 616204-22-9
Acetyl Hexapeptide-8, also known as Argireline®, is a widely used anti-wrinkle cosmetic peptide designed to reduce facial expression lines. It is one of the most recognized non-injection alternatives to Botox-style anti-aging treatments.
- Product Introduction
What Is Acetyl Hexapeptide-8 (CAS 616204-22-9)?
Acetyl Hexapeptide-8, also known as Argireline®, is a widely used anti-wrinkle cosmetic peptide designed to reduce facial expression lines. It is one of the most recognized non-injection alternatives to Botox-style anti-aging treatments.
Acetyl Hexapeptide-8 is a synthetic peptide derivative of SNAP-25, a protein involved in neurotransmitter release. Because of its ability to relax facial tension, it is commonly used in formulations that target dynamic wrinkles, such as those around the eyes, forehead, and mouth.
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Item |
Details |
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INCI Name |
Acetyl Hexapeptide-8 |
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CAS Number |
616204-22-9 |
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Molecular Weight |
~ 888.0 g/mol |
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Appearance |
White/off-white lyophilized powder |
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Purity |
≥98% (HPLC) |
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Application |
Anti-wrinkle, skincare, anti-aging formulations |
How Acetyl Hexapeptide-8 Works?
Reduces Facial Muscle Contraction
The peptide interferes with SNAP-25, a component of the SNARE complex involved in neurotransmission.
This leads to reduced muscle contraction, softening expression lines.
Decreases the Depth of Dynamic Wrinkles
Especially effective for wrinkles caused by repetitive facial movements:
Crow's feet
Forehead lines
Frown lines
Smile lines
Non-invasive "Botox-like" Mechanism
Provides a topical alternative to injectable neuromodulators.
Enhances Skin Smoothness & Texture
Regular use leads to smoother, firmer-looking skin.
Acetyl Hexapeptide-8 CAS 616204-22-9 Benefits
- Reduces the depth and visibility of expression wrinkles
- Provides a Botox-like effect without injections
- Improves skin smoothness, firmness, and tone
- Works well around the eyes, forehead, and mouth
- Fast-acting and suitable for daily use
- High safety profile for all skin types
Comparison With Other Peptides
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Peptide |
Main Function |
Best For |
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Acetyl Hexapeptide-8 |
Muscle-relaxing, wrinkle reduction |
Expression lines |
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Palmitoyl Tripeptide-1 |
Collagen stimulation |
Firming, regeneration |
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Matrixyl 3000 |
Anti-aging complex |
Deep wrinkles |
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GHK-Cu |
Repair + anti-inflammatory |
Skin healing + rejuvenation |
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