Aviptadil Acetate VIP CAS 40077-57-4 For Gut Health

Aviptadil Acetate (CAS 40077-57-4), also known as Vasoactive Intestinal Peptide (VIP), is a naturally occurring neuropeptide widely researched for its role in intestinal function, mucosal balance, and gastrointestinal signaling. The synthetic form provided is produced with high purity, making it suitable for studies involving gut health, epithelial protection, and digestive-system physiology.

Send Inquiry

Product Introduction

Aviptadil Acetate (VIP) – CAS 40077-57-4 | High-Purity Vasoactive Intestinal Peptide for Gut Health Research

VIP is broadly distributed throughout the body and is especially present along the gastrointestinal tract. This 28–amino acid polypeptide shares structural similarities with secretin and glucagon. In biological systems, VIP is known to promote vasodilation, enhance cardiac contractility, stimulate bicarbonate secretion, relax gastrointestinal and other smooth muscles, support glycogenesis, suppress gastric acid secretion, and stimulate insulin release. Its dual function as both a hormone and a neurotransmitter has been extensively examined in scientific research.

Specifications

Property	Value
CAS	40077-57-4
Synonyms	Vasoactive Intestinal Peptide, VIP
Molecular Weight	3357.9 g/mol
Sequence	HSDAVFTDNYTRLRKQMAVKKYLNSILN
Appearance	White to off-white powder
Solubility	Water, PBS, or compatible buffers
Storage	–20°C (long-term)
Grade	Research / Laboratory Use Only

Aviptadil Acetate Benefits

01/

-Supports studies on gut motility, mucosal balance, and gastrointestinal function.

02/

-Useful for investigating smooth muscle relaxation and vasodilation pathways.

03/

-Enables research on VIP receptor activity (VPAC1/VPAC2).

04/

-Applied in studies related to metabolic signaling and insulin pathways.

05/

-Provides consistent, high-purity results for peptide and physiology research.

Aviptadil Acetate Mechanism of Action

Aviptadil Acetate works by binding to VPAC1 and VPAC2 receptors, activating the cAMP signaling pathway. This leads to relaxation of smooth muscle, modulation of gastrointestinal secretions, vasodilation, and regulation of hormone release such as insulin. As a neuropeptide, it also participates in enteric nervous system signaling and supports studies on epithelial and immune responses.

Research Applications

Researchers commonly include Aviptadil in studies of:

Pulmonary physiology and airway/vascular reactivity

Inflammatory and immunomodulatory pathways in lung tissue models

Vascular biology and endothelial function assays

Ex vivo organ/tissue experiments exploring bronchodilation or vasodilation

Mechanistic studies of peptide-receptor signaling (VPAC1/VPAC2)

Note: Use Aviptadil in controlled laboratory settings and follow institutional protocols for peptide handling.

We are a trusted Chinese peptide manufacturer and exporter, providing premium-grade Aviptadil Acetate (VIP) CAS 40077-57-4 for research institutions focused on GH modulation, fat metabolism, and bodybuilding peptide studies.

Pls feel free to contact Vic for any questions:

Whatsapp: +852 9433 2308

Telegram: Your Telegram

Email: Jdy_gsyg@163.com

Our Advantages

End-to-End Peptide Production Capabilities

We provide a fully integrated manufacturing process-from solution preparation using stainless steel mixing tanks, sterile filtration via ultrafiltration systems, aseptic filling under laminar flow hoods, to lyophilization under strict temperature and pressure control. This ensures high purity, stability, and sterility of our peptide products, meeting stringent pharmaceutical and biotech industry standards.