Abarelix Acetate CAS 183552-38-7

 

What is Abarelix Acetate (CAS 183552-38-7)?
Abarelix Acetate is a synthetic peptide GnRH (gonadotropin-releasing hormone) antagonist designed to rapidly suppress hormone production. By directly blocking GnRH receptors in the pituitary gland, it inhibits the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to significant reductions in testosterone and estrogen levels.
This unique mechanism makes Abarelix Acetate highly valuable in oncology and endocrinology research, especially in studies involving hormone-dependent cancers and Abarelix Acetate testosterone suppression models.

 

 

We utilize sterile sealing and capping processes to minimize microbial contamination and prevent microbial interference with reactions, ensuring synthesis efficiency and product stability. We also utilize advanced instrumentation, including high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS). From integrated production to quality control, we ensure high-quality products.

 

 

Parameter	Specification
CAS Number	183552-38-7
Molecular Formula	C₇₂H₉₅Cl₂N₁₇O₁₄·C₂H₄O₂ (Acetate salt)
Molecular Weight	1656.6 g/mol
Purity	≥98% (HPLC verified)
Appearance	White to off-white powder
Solubility	Soluble in water, acetic acid, DMSO
Storage	-20°C, protected from light & moisture
Shelf Life	24 months when stored properly
Sterility	Sterile-filtered (upon request)
Grade	Research/Pharmaceutical

 

 

Abarelix Acetate functions as a direct GnRH receptor blocker:

Prevents GnRH from activating pituitary receptors

Reduces LH & FSH secretion

Results in rapid testosterone suppression and lower estrogen production

Unlike GnRH agonists, Abarelix avoids the initial hormone surge (flare effect), making it suitable for research models that require immediate androgen deprivation.

 

 

-Rapid Hormone Suppression: Unlike agonists, it avoids the initial testosterone flare effect.

-Prostate Cancer Treatment: Used in advanced prostate cancer to lower androgen levels quickly.

-Research Applications: Valuable in endocrinology and oncology studies.

-Controlled Hormone Modulation: Ideal for Abarelix Acetate testosterone suppression protocols

 

 

Feature	Abarelix Acetate	Leuprolide (GnRH Agonist)	Degarelix (GnRH Antagonist)
Mechanism	GnRH Antagonist	GnRH Agonist (flare effect)	GnRH Antagonist
Onset of Action	Rapid suppression	Delayed (after flare)	Rapid suppression
Hormone Surge	No	Yes (initial increase)	No
Applications	Prostate cancer, research	Prostate cancer, endometriosis	Prostate cancer

 

 

 

 

Abarelix Acetate CAS 183552-38-7 is a potent GnRH antagonist that enables fast and sustained testosterone suppression without flare effects. It is a valuable compound in oncology, endocrinology, and hormone-dependent disease research.

 

 

• High Purity (≥98%) – Rigorous QC testing
• Competitive Pricing – Factory-direct supply
• Fast & Secure Shipping – Global delivery options
• Custom Synthesis – Bulk quantities available
• 24/7 Technical Support – Expert guidance

 

 

Looking to source Abarelix Acetate peptide (CAS 183552-38-7) for your lab or project? Get in touch with our sales team for quotes, availability, and technical specifications.

 

 End-to-End Peptide Production Capabilities

 

 

 

 

 

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